Simplify tablet formulation evaluation with a manufacturability profile

by Michael Gamlen Gamlen Tableting Ltd, Biocity Nottingham, Pennyfoot Street, Nottingham NG1 1GF Summary Development of a manufacturability protocol for laboratory use is an important process of developing tablet formulations and managing tablet quality. The manufacturability protocol developed for use on a simple laboratory instrument can be used throughout the …

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Strong interest in Gamlen D series at European Pharmaceutics Conference

Gamlen Instruments exhibited at the recent 2nd European Pharmaceutics Conference in Kraków, Poland. Visitors from across Europe expressed great interest in the D series powder compaction analyzer, attracted by the simplicity of the Gamlen® Manufacturability Assessment. The Gamlen® Manufacturability Assessment enables users to make a simple assessment of powder properties …

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Application studies using the Gamlen D series at an excipient manufacturer’s laboratory

    Key purpose: Formulation screening before transfer to rotary press – saving material. Four studies include:   Correlation of Gamlen D series and Romaco Kilian Pressima Rotary Press Application in formulation development (lubricant optimization) Analysis of SiO2 addition to excipient and testing tablet hardness Analysis of elastic recovery and …

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Early processability assessments during product development can help identify optimal API for efficient processing

Downstream processability of crystal habit-modified active pharmaceutical ingredient   Authors Nawin Pudasaini† Pratik P Upadhyay† Christian R Parker‡ Stefan U Hagen‡ Andrew D Bond†§ and Jukka Rantanen*† †Department of Pharmacy, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, Copenhagen, Denmark ‡Syntese A/S, Industriholmen 11-13, Hvidovre, Denmark §Department …

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Gamlen Instruments exhibiting at the 2nd European Conference on Pharmaceutics, Krakow, 3-4 April 2017

Gamlen Instruments will be exhibiting at the forthcoming 2nd European Conference on Pharmaceutics and presenting a poster entitled “Use of a manufacturability profile to simplify tablet formulation evaluation”. During the conference, Gamlen Instruments will be demonstrating the Gamlen D series dynamic powder compaction analyzer for advanced tableting research and development. The D …

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What you didn’t know about breakage of anisotropic rod-shaped particles

Authors: V Penkavova1*, L Kulaviak1, MC Ruzicka1, M Puncochar2, P Zamostny3 1 Department of Multiphase Reactors, Institute of Chemical Process Fundamentals, Czech Academy of Sciences, Prague, Czech Republic, 2 Environmental Process Engineering Laboratory, Institute of Chemical Process Fundamentals, Czech Academy of Sciences, Prague, Czech Republic, 3 Department of Organic Technology, …

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Characterization of tableting properties measured with a multi-functional compaction instrument for several pharmaceutical excipients and actual tablet formulations

Authors Takashi Osamuraa,b Yoshiko Takeuchia Risako Onoderaa Masahiro Kitamurab Yoshiteru Takahashib Kohei Taharaa Hirofumi Takeuchia,* a Laboratory of Pharmaceutical Engineering, Gifu Pharmaceutical University, 1-25-4 Daigaku-Nishi, Gifu 501-1196, Japan b Pharmaceutical Technology Department, Sawai Pharmaceutical Co. Ltd, 12–34, Hiroshibacho, Suita-Shi, Osaka 564-0052, Japan Summary Before designing tablet formulations, it is important …

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Gamlen R series featured in International Journal of Pharmaceutics paper

Characterization of tableting properties measured with a multi-functional compaction instrument for several pharmaceutical excipients and actual tablet formulations is the latest paper to be published in the International Journal of Pharmaceutics detailing research undertaken using a Gamlen instrument (IJP 510(2016) 195-202). Authored by leading tableting researcher Takashi Osamura with Yoshiko Takeuchi, Risako Onodera, …

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Gamlen Tableting to exhibit at the 2016 AAPS Annual Meeting and Exposition

Gamlen Tableting will be exhibiting at the forthcoming American Association of Pharmaceutical Scientists Annual Meeting and Exposition (AAPS 2016), 13th-17th November, at the Colorado Convention Center, Denver (Booth Number 868). We will be demonstrating Gamlen Tableting’s new manufacturability protocol which utilises data captured by the Gamlen D Series Powder Compaction …

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Fellowship awarded to Michael Gamlen

Michael Gamlen has been made a Fellow of the Academy of Pharmaceutical Sciences of Great Britain in recognition of his international reputation in the field of tableting research and development; a decision that received the full support of the APS Board of Trustees. With over 30 years pharmaceutical industry experience, Michael …

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Gamlen Tableting attending EuPAT8, 3rd-4th October, Cork, Ireland

Gamlen Tableting will be presenting a poster at EuPAT8, the 8th pan-European Science Conference on Quality by Design (QbD) and Process Analytical Technology (PAT) Sciences conference. The meeting brings together pharmaceutical scientists and engineers from industry, academia and regulatory agencies to discuss recent developments and future trends in the field …

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