Authors Takashi Osamuraa,b Yoshiko Takeuchia Risako Onoderaa Masahiro Kitamurab Yoshiteru Takahashib Kohei Taharaa Hirofumi Takeuchia* a Laboratory of Pharmaceutical Engineering, Gifu Pharmaceutical University, 1-25-4 Daigaku-Nishi, Gifu 501-1196, Japan b Pharmaceutical Technology Department, Sawai Pharmaceutical Co. Ltd, 12-34, Hiroshibacho, Suita-Shi, Osaka 564-0052, Japan Summary We previously determined “Tableting properties” by using …
by Hanna Kotłowska and Małgorzata Sznitowska Department of Pharmaceutical Technology, Medical University of Gdańsk, Al. Hallera 107, 80-416 Gdańsk, Poland Introduction Lorazepam is commonly used for sedation in pediatric and neonatal intensive care units and in the treatment of status epilepticus. However, for children under 12 years of age, injection …
Since then the Gamlen tablet press has been developed into 3 key products:
1. Gamlen M series for small scale tablet manufacturing
Custom small-batch tablet manufacturing with portable benchtop flexibility for your laboratory or manufacturing facility.
2. Gamlen R series for entry level research and development
Tableting research and development systems for scientists in academia and industry.
3. Gamlen D Series For Advanced Research And Development
Advanced Tableting Research With Affordable In-Die Dynamic Compaction Analysis For Industry And Academic Professionals.
This video explains how the relationships between compaction pressure, tensile strength and solid fraction are studied using the compaction triangle.
Tablet hardness, or breaking strength, is an important and widely used parameter to control the tablet manufacturing process. In many cases it is used as a surrogate measure for compression force during manufacture, particularly if the tablet press is unable to measure compression force.
It is an important control parameter because compression affects every tablet property including disintegration, dissolution and friability. In some cases stability is also affected.
Watch video for full explanation
“One of the problems in creating the course is designing an experiment that will deliver reproducible results so that the students can generate models from the data. During trialling, we quickly found that the Gamlen R series generated consistent results and allowed control of variables which made the Gamlen R …