Helping you make better tablets using advanced material testing

Small scale tablet manufacture

The reliable way to study formulation properties and predict how they’re going to perform in the manufacturing process

 

For over a century pharmaceutical manufacturers struggled with powder compression problems such as capping and lamination, powder sticking to punch surfaces or die wall, and insufficient mechanical strength to withstand stress in downstream processing.

Taking the guesswork out of tablet manufacturing assessments

Now there is a new laboratory tablet testing service to help you predict and avoid common manufacturing problems. This gives you the peace of mind that your formulation works and your material is the same quality as previous batches.

This will speed up your manufacturing process, reduce material costs and save you time and money. The service is ideal for manufacturers of generic products and vitamin supplements.


Choose from three levels of material testing:

1. Gamlen Manufacturability Assessment

You send us your material samples and we will make a simple assessment of powder properties based on small batches of tablets compressed under tightly controlled conditions using the Gamlen D series Powder Compaction Analyzer. The results will be compiled into a report and emailed to you.

Cost £500 exc VAT  Order now


2. Enhanced Manufacturability Assessment

The enhanced service offers all of the above plus a detailed analysis of powder properties including Heckel and Kawakita plots.

Cost £1000 exc VAT  Order now


3. Advanced Manufacturability Assessment

Includes dry granulation evaluation (two enhanced tests)

Cost £2000 exc VAT  Order now


What happens next?

 

Once we have received your material samples, we will send you a confirmation email and begin testing.
You will then receive an email report with recommendations within 10 days.

We are happy to discuss the results with you over the telephone.


How is the material testing and analysis carried out?

 

The Gamlen Manufacturability Assessment enables users to make a simple assessment of powder properties based on small batches of tablets compressed under tightly controlled conditions using the Gamlen D series Powder Compaction Analyzer.

A batch of 15 or 25 tablets is prepared, three or five tablets at each of five compaction pressures. The tablets are broken in diametral compression, preferably using the Gamlen Tablet Tensile Analyzer (TTA). The data is copied into a spreadsheet, which then analyses the key Manufacturability attributes relating to compaction and lubrication, and automatically produces/tablets based on well-established literature values for the tablet key properties. Full data are also presented so that the user can, if desired, make their own analysis of the findings.

We recommend collecting data on all development tablet samples to provide a database of information. This can be used at the early stages of development to assist in the evaluation of drug substance batches, formulas and processes.

It also forms a basis against which future batches of product can be assessed for consistency during process development, technology transfer and routine production.

The data set will be invaluable for identifying changes and trends in the manufacturing process as it is scaled up and put into production.


Enhanced Manufacturability Assessment for given sample

 

The enhanced service offers all of the above plus a detailed analysis of powder properties including Heckel and Kawakita plots.


Advanced Manufacturability Assessment for given sample

 

Includes Assessment 1 plus two dry granulation evaluation tests.


Order form




Select service



Comments are closed