Gamlen Powder Compaction Analysis System PCA-500
Dramatically speeds formulation development
and process optimisation

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Now you can see the effect of formulation and process variations on tablet compaction prior to manufacturing. The PCA-500 allows you to automatically generate tablet tensile fracture stress, compactibility, compressibility and tabletability plots with no user input needed. You can also generate Kawakita and Heckel plots with 1 μm accuracy.

Benchtop compaction analysis
including in-die and out-of-die measurements

The PCA-500 provides complete analysis of the compaction process using an affordable benchtop system. It measures compaction force, punch position, and ejection force. Compaction rate is 0.01-3 mm/s with 90 ms dwell time. Also available with optional fully integrated detachment force measurement (PCA-500D, shown).

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Overview

 

The Compaction Analysis System PCA-500 comprises of the Gamlen Powder Compaction Analyzer (PCA) and Tablet Tensile Analyzer (TTA). The TTA comes with a 4-figure analytical balance and electronic micrometer. The included software runs on a laptop and displays all data for automatic analysis via a spreadsheet.

Integrated detachment force measurement (PCA-500D)

The new rotatable die system simplifies operation and generates important new data at the same time. The operational sequence is completed entirely on the instrument using the load cell to detach as well as eject the tablet. The result is detailed measurement of tablet compaction, detachment and ejection behaviour.

Tablet Tensile Analyzer

The Tablet Tensile Analyzer has been specially developed to simplify the evaluation of tablet samples made on the PCA-500. It is a modified tablet tensile tester combined with a 4-figure analytical balance and electronic micrometer.

Tablet fracture is performed at slow speed to generate true tensile fracture stress measurements. The computer control system captures all data and presents it in a spreadsheet for automatic analysis.

Tablet measurements
Weight
Thickness
Diameter
Breaking strength

Calculated values
Tablet density
Tablet tensile fracture stress
Solid fraction

The system produces plots of tablet solid fraction vs tensile fracture stress (compactibility). When used in conjunction with the PCA-500, plots of tabletability (compaction pressure vs tensile strength) and compressibility (compaction force vs solid fraction) are also automatically generated.


Unique benefits

 

  • See the effect of formulation and process variations on tablet compaction
  • Automatically generate tablet tensile fracture stress, compactibility, compressibility and tabletability plots with no user input needed
  • Dramatically speeds formulation development and process optimisation
  • Generates Kawakita and Heckel plots with 1 μm accuracy

Key features

 

  • Complete analysis of the compaction process using benchtop system including compaction force, punch position, and ejection force. Detachment force option available
  • Compaction rate 0.01-3 mm/s with 90 ms dwell time
  • Now available with optional fully integrated detachment force measurement (PCA-500D, shown)

Specification of powder compaction analyzer

 

Tablet punch size

2-15 mm diameter

Material capacity of the die

2-400 mg

Compaction rate

0.01-3 mm/s

Maximum load

500 kg

Load cell travel

30 mm

Test height

Depends on pillar extension length.
Maximum extension of 300 mm

Load selection

User selected by computer interface

Load cell resolution

1:5000

Calibration

Dead weights in kg or proving ring

Power requirements

110/240 VAC 3.15 A

Instrument dimensions

310(w) x 270(d) x 375(h)

Instrument weight

16 kg

Shipping size

390 x 350 x 390 or 460 x 430 x 480

Shipping weight approx

20 kg
Optional detachment force measurement system available

Tablet Tensile Analyzer shadow 800 px (w)Gamlen Tablet Tensile Analyzer

 

The Tablet Tensile Analyzer has been specially developed to simplify the evaluation of tablet samples made on the PCA-500. It is a modified tablet tensile tester combined with a 4-figure analytical balance and electronic micrometer.

Tablet fracture is performed at slow speed to generate true tensile fracture stress measurements. The computer control system captures all data and presents it in a spreadsheet for automatic analysis.


Learn more about the Gamlen Tablet Tensile Analyzer

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