Early processability assessments during product development can help identify optimal API for efficient processing

Downstream processability of crystal habit-modified active pharmaceutical ingredient   Authors Nawin Pudasaini† Pratik P Upadhyay† Christian R Parker‡ Stefan U Hagen‡ Andrew D Bond†§ and Jukka Rantanen*† †Department of Pharmacy, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, Copenhagen, Denmark ‡Syntese A/S, Industriholmen 11-13, Hvidovre, Denmark §Department…

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How to make a good tablet
and avoid common tableting problems

Determining whether a powder will form a good tablet is a complex process because for a material to make a good tablet it requires a number of different attributes which in some ways conflict with each other. For example it needs to be well lubricated but also to be easily…

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Reducing risk in tablet development and manufacture

Study carried out using Gamlen Tablet Press This article describes how measuring material properties that relate directly to the final tablet product, including the inherent ability of materials to form tablets (compressibility) reduces the overall risk in tablet development and manufacture. A case study illustrates the benefits of rapid compressibility…

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